Irregular Sleep May Lead to Cancer Risk, Even Heart Disease

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VIVA – Based on a seven-year study of middle-aged and older adults, people who have irregular sleep may lead to cancer risk and even heart disease, compared with people who have regular sleep schedules. 

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"To my knowledge, our study is the largest to look at how sleep irregularity affects all-cause mortality," or death from any cause, Matthew Pase, an associate professor of psychology at Monash University in Australia and a co-author of the study. 

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Sleep regularity may impact mortality independently of sleep duration, he added. 

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Pase and his colleagues recruited nearly 90,000 people living in the UK to wear movement-tracking devices on their wrists for around a week; the participants ranged from about 40 to 70 years old. 

By using a statistical model to estimate when people were asleep or awake from the recorded movement data, the researchers calculated a sleep regularity score for each participant, defined as the probability that a person was awake or asleep at the same time between any two consecutive days. 

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One group of participants was scored as having "low sleep regularity," as they had a 41% chance of being asleep or awake at the same time for two days in a row; this put the group in the fifth percentile of sleep scores, overall. Those with "average" sleep regularity, who were in the 50th percentile, had a 61% chance of being asleep at the same time on consecutive days.

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Within about seven years of the team collecting this data, 3,010 of the participants died. Those with low sleep regularity scores were 46% more likely to die of any cause within the follow-up period, compared with people with average scores. 

Of the people who died, 1,701 died of cancer, and 616 died of cardiovascular disease. People with low sleep regularity scores were 33% more likely to die of cancer, and 73% more likely to die of cardiovascular disease, than people with average scores. 

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