First UK Baby Born with DNA from Three Different People
- https://www.mustelausa.com/
So-called reversion or reversal could lead to a disease in the child. “The reason why reversal is seen in the cells of some children born following MRT procedures, but not in others, is not fully understood,” said Dagan Wells, a professor of reproductive genetics at the University of Oxford who took part in the research.
Ilustrasi bayi.
- ISTOCK/BBC.com
Women with mitochondrial mutations can avoid passing on disorders by adopting or having IVF with a donor egg. Or, to have genetically related children, affected women can have their IVF embryos screened for mitochondrial mutations.
Though effective in many cases, this reduces the risk rather than removing it completely, and it cannot help when all of the embryos a woman produces have highly mutated mitochondria.
The UK is not the first country to create babies from MDT. In 2016, a US doctor announced the world’s first MDT birth after treating a Jordanian woman who carried mitochondrial mutations that cause a fatal condition called Leigh syndrome.
Before the treatment, performed in Mexico, the woman had four miscarriages and two children. One died aged six, the other lived for only eight months.